Real-Time analysis of exosome secretion of single cells with single molecule imaging

The exosome-mediated response can promote or restrain the diseases by regulating the intracellular pathways, making the exosome become an effective marker for diagnosis and therapeutic control at the single-cell level. However, real-time analysis is hard to be achieved with traditional approaches because the exosomes usually need to be enriched by ultracentrifugation for a measurable signal-to-noise ratio. Recently developed label-free single-molecule imaging approaches may become an real-time quantitative tool for the analysis of single exosomes and related secretion behaviors of single living cells owing to their extreme sensitivity.     

煤矿立井提升机新型盘形制动器的应用分析

盘形制动器属于提升系统内的一重要部件,为确保提升机盘形制动器的稳定可靠运行,基于同家梁矿矿井提升机盘形制动器应用现状,分析了现存的主要问题,提出了采用智能监测盘形制动器来替代原盘形制动器的策略.通过在该新型盘形制动器内装设内置制动正压力传感器,解决了老旧盘形制动器无法准确测量内部碟簧力的问题,取得了较好的应用效果.     

一种大量元素水溶肥料的制备及其在玉米上的喷施效果

根据玉米需肥特性设计氮磷钾比例,制备了含中微量元素的大量元素水溶肥料,产品氮、磷、钾比例为2∶1∶4,属于高钾中氮低磷型.在河北省安平县前子文村和浙江省新昌县孟家塘村玉米上开展了叶面喷施试验.结果表明:玉米生物学性能得到改善,玉米产量、出籽率、百粒重与容重得到提高;与空白对照相比,平均增产率为5.45％,平均纯增收896.40元/公顷,平均产投比为5.43∶1.     

高分子材料导热性能影响因素研究进展

介绍了高分子材料导热性能影响因素研究进展，重点阐释了聚合物基体的结构特性（链结构、分子间相互作用、取向、结晶度等）、导热填料（种类、含量、形态、尺寸等）以及制备方法等对高分子材料导热性能的影响。     

虚实结合的可穿戴产品适合性检验研究

目的 为了更科学地研究和检验可穿戴产品的适合性,提出一种适合性检验方法,能够精确保留现实环境中的产品佩戴关系,并能将现实与虚拟的适合性检验研究相结合,得到合理的适合性检验结果.方法 以虚拟现实眼镜的适合性检验为例,通过高精度的三维测量技术将现实环境中的人、产品以及人—产品佩戴关系转化为三维虚拟信息,并以人—产品佩戴三维模型为参考基准对齐人和产品的虚拟模型,得到保留现实佩戴关系的人—产品佩戴模型组,再应用偏差分析法得出人—机佩戴区域的可视化适合性结果和统计数据,结合主观评价方法进一步分析产品的适合性.结论 虚实结合的产品适合性检验方法可在虚拟环境中高精度地保留现实环境中的人—产品佩戴关系,并能得到可视化的适合性检验结果,为检验和指导产品的适合性提供依据.     

Effects of Different Short-Term UV-B Radiation Intensities on Metabolic Characteristics of Porphyra haitanensis

The effects of ultraviolet (UV) radiation, particularly UV-B on algae, have become an important issue as human-caused depletion of the protecting ozone layer has been reported. In this study, the effects of different short-term UV-B radiation on the growth, physiology, and metabolism of Porphyra haitanensis were examined. The growth of P. haitanensis decreased, and the bleaching phenomenon occurred in the thalli. The contents of total amino acids, soluble sugar, total protein, and mycosporine-like amino acids (MAAs) increased under different UV-B radiation intensities. The metabolic profiles of P. haitanensis differed between the control and UV-B radiation-treated groups. Most of the differential metabolites in P. haitanensis were significantly upregulated under UV-B exposure. Short-term enhanced UV-B irradiation significantly affected amino acid metabolism, carbohydrate metabolism, glutathione metabolism, and phenylpropane biosynthesis. The contents of phenylalanine, tyrosine, threonine, and serine were increased, suggesting that amino acid metabolism can promote the synthesis of UV-absorbing substances (such as phenols and MAAs) by providing precursor substances. The contents of sucrose, D-glucose-6-phosphate, and beta-D-fructose-6-phosphate were increased, suggesting that carbohydrate metabolism contributes to maintain energy supply for metabolic activity in response to UV-B exposure. Meanwhile, dehydroascorbic acid (DHA) was also significantly upregulated, denoting effective activation of the antioxidant system. To some extent, these results provide metabolic insights into the adaptive response mechanism of P. haitanensis to short-term enhanced UV-B radiation.     

污水处理场废气生物处理装置提标

VOCs是形成臭氧的重要前体物,加强VOCs治理是现阶段控制臭氧污染的有效途径.废气生物处理装置为满足新的排放要求改造前应先对废气组分进行分析,并筛选合适的菌种进行接种以降低后续提标装置的投资.可采用吸附技术或高级氧化技术对生物处理装置出气进行提标处理.提标工艺如采用吸附技术需考虑吸附剂脱附产生物质的再处理.     

浅析钛及钛合金在海洋装备上的应用

钛及钛合金在海洋工程装备领域应用非常广泛，如船体结构件、潜艇和深潜器的耐压壳体、管件、阀及附件、动力驱动装置中的推进器、冷凝器、冷却器、换热器、舰船声呐导流罩、螺旋桨等。本文在介绍钛及钛合金在海洋装备领域应用特点的基础上，总结了目前国内外形成的舰船用钛及钛合金体系和性能特征，分析了国内外钛及钛合金在海洋装备领域的应用现状及优势，展望了钛材在海洋装备的应用前景，以期对后续海洋工程装备设计选材提供参考，从而大幅度加速推动钛材在我国海洋装备领域的应用。